Point and interval estimation via likelihood; likelihood-ratio tests; use of pivotal quantities; sufficient statistics and Rao-Blackwell Theorem; ancillary statistics; computational aspects, including Newton-Raphson iteration, iteratively-reweighted least-squares, EM algorithm, profile likelihood.
Prerequisites
Fundamentals of estimation and hypothesis-testing at the level of Chapters 8, 9 and 10 of Wackerly, Mendenhall and Scheaffer, Mathematical Statistics with Applications (5th edition, 1996, Duxbury).